Shinichi Takeda
National Institute of Neuroscience, Japan
Biography
Shin’ichi Takeda is currently the Director General of National Institute of Neuroscience in the National Center of Neurology and Psychiatry (NCNP). He initially trained as a Clinical Neurologist and received a PhD degree in Muscle Biology from Shinshu University, Graduate School in 1981 and has a long time laboratory experience including Paris Pasteur Institute (1987-1992). He focused his research on development of molecular therapy of Duchenne muscular dystrophy (DMD), since he came back from France and has gotten the position in NCNP in 1992. He has showed a proof of concept study of exon skipping in the colony of dystrophic dogs that he established and he recently finished the early phase clinical trial of exon 53 skipping of the dystrophin gene among DMD patients in Japan as a PI. He is working as an Associate Editor for review of J. Neuromuscular Diseases since 2013 and an Associate Editor of Am. J. Pathology since 2014.
Abstract
Abstract : On-going exon 53 skipping clinical trial for Duchenne Muscular Dystrophy